By Leonard Berliner, Heinz U. Lemke
This publication explores how PPPM, scientific perform, and simple study can be top served by way of info know-how (IT). A use-case was once constructed for hepatocellular carcinoma (HCC). the topic used to be approached with 4 interrelated projects: (1) evaluation of medical practices when it comes to HCC; (2) suggest an IT process with regards to HCC, together with medical choice aid and study wishes; (3) ensure how a medical liver melanoma heart can give a contribution; and, (4) research the improvements and effect that the 1st 3 projects may have at the administration of HCC. An IT approach for custom-made medication (ITS-PM) for HCC will give you the capability to spot and make sure the relative worth of the large variety of variables, together with scientific evaluate of the sufferer -- practical prestige, liver functionality, measure of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic point; tumor burden and person sufferer reaction; clinical and operative remedies and their outcomes.
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Extra resources for An Information Technology Framework for Predictive, Preventive and Personalised Medicine: A Use-Case with Hepatocellular Carcinoma
Due to its aggressive nature and poor survival rate, incidence and mortality rates are almost equivalent, accounting for approximately 500,000 deaths annually . Since HCC is most often seen in patients with chronic liver disease or cirrhosis, the incidence of HCC and the epidemiology of underlying liver diseases are closely linked. HCC diagnosed after the onset of symptoms portends a poor prognosis with a 5-year survival of 0– 10 %, highlighting the importance of screening for HCC in high risk patients and early treatment.
3 Generic PSM constellation grid showing first order information entities all orders. Linkages between any entity, of any order, (on the y-axis) and an associated TIMMS Component (on the x-axis) may be displayed as needed. The attributes defining the DPM will change over time, especially during the course of a medical treatment or surgical intervention. It is one of the roles of the DPM and associated software tools to gather, calculate, record, tabulate, or otherwise organize, maintain, and communicate values for each of these entities, and to predict and record the changes in values brought about through the interactions with the entities.
1) is provided for the flow of patients, who present from a variety of sources with a possible liver tumor. The patient will first be evaluated by their primary care physician, or in absence of this, be a member of the medical team of the CLCC. At times the patient may be referred directly to the Medical Oncologist, Oncological Surgeon, Interventional Radiologist, or Radiation Oncologist. Presentation at Tumor Board and multi-specialty clinical cancer conferences is of extreme importance since a multi-disciplinary approach is essential for optimal treatment planning for each patient.
An Information Technology Framework for Predictive, Preventive and Personalised Medicine: A Use-Case with Hepatocellular Carcinoma by Leonard Berliner, Heinz U. Lemke